Endocrine Abstracts

Prolactinoma represents 27 to 35% of pituitary adenomomas and 40 to 75% of secreting adenomas. However, the macroprolactinomas are not frequent. We report clinical, biological and therapeutic aspects of 5 cases of macroprolactinomas. It concerns 3 women and 2 men. The average age is 43.4 years (19–68). The reason for seaking medical advice was amenorrhea – galactorrhea syndrom in 2 women and infertility in one case. The diagnosis of pituitary adenoma is incidentally ...

Introduction: Hemochromatosis is a disorder caused by an excess of iron deposition in the parenchymal cells that leads to organ dysfunction. In patients with secondary hemochromatosis due to multiple blood transfusions, endocrinopathies such as diabetes mellitus, hypopituitarism frequently develop.Herein we report the case of a patient with B-thalassemia major who developed diabetes mellitus, hypopituitarism and primary hypoparathyroidism due to secondar...

Introduction: Mixed gonadal dysgenesis with 45X/46XY mosaicism is considered to be a rare disorder of sex development. This condition is characterized by a phenotypically very heterogeneous clinical presentation. In fact, the individuals with 45X/46XY mosaicism ranged from phenotypically normal men with azoospermia, going through individuals with genital ambiguity, to women with Turner syndrome.Herein, we describe a phenotypically Turner-like female with...